#64643
just some quick research...
Pituitary (Pituitary Gland)
The pituitary gland is a small (half-inch), bean-shaped organ that hangs down from the lower center of the brain on a stalk attached to another gland, the hypothalamus. Weighing less than one gram, the pituitary gland is often called the "master gland" since it controls the secretion of hormones by other endocrine glands. It regulates many body activities, and is partitioned into front and back lobes. The front lobe is stimulated by the hypothalamus, and produces any one of six different hormones that in turn stimulate the thyroid, adrenal and reproductive glands, and also breast milk production.
Poor Slow Wound Healing
Complications are more likely to develop in aging skin, such as the progression of a wound to a chronic non-healing state. This is related to an increased amount of elastase in the wound. Elastase is an enzyme that breaks down elastic proteins and is upregulated in impaired wound healing states. In a study [Ashcroft et al. 1999] involving 36 patients over the age of 70, half male and half female, topical estrogen was found to decrease delays in wound healing in both the male and female patients. Wound size, collagen levels, and fibronectin levels all improved with topical estrogen, indicating improved wound healing. In this study, estrogen was delivered to the wound site for 24 hours as a patch routinely used in female estrogen replacement therapy. Fibronectin levels have been found to be deficient in chronic wounds of the aged, such as venous ulcers in humans or laboratory wounds in aged animals [Herrick et al. 1997].
http://www.diagnose-me.com/treat/T484394.html
According to that "elastase" is something to look into as a cause for not healing and topical estrogen for treatment.