Re: Lipase: the enzyme that breaks down fat

http://www.patentstorm.us/patents/6869603-description.html

Of particular interest is the use of lipoprotein lipase in the treatment of inflammatory conditions of the skin such as Psoriasis or sunburn. Interaction of the enzyme with substrates of monoglycerides, diglycerides or triglycerides leads to the generation of free fatty acid and MAG ligands and to the subsequent activation of the PPAR-alpha receptor. The major source of fatty acids from plant and animal origin are triglycerides, lipid particles consisting of three fatty acids esterified to a glycerol backbone. Triglycerides represent the most common natural store of stable fatty acids esters. Free fatty acids represent lipophylic compounds that have limited permeability through the skin barrier. These fatty acid compounds, when in their free form, rapidly undergo esterification, oxidation and other reactions that reduce or eliminate their effectiveness, and induce wide array of separate and likely competing biologic effects, including pro-inflammatory reactions. The generation of these fatty acid compounds through LPL immediately before their uptake by the skin circumvents such modifications while still leading to activation of PPAR pathways. Thus, one important feature of the present invention is that enzyme and substrate are not combined until immediately before compositions are applied. By keeping these components separate until the time of therapy, enzyme activity can be better maintained and free fatty acids and MAG are made available to cells for PPAR? activation. (Topical application of lotions containing Lipase)




http://www.enzymedica.com/faq.php
(THIS IS A GOOD ONE:)

8. What enzymes should I take for proper digestion?
Protease breaks down protein, amylase breaks down carbohydrate and starch, and lipase breaks down fat. These three enzymes break down the majority of the type of food you eat. Added to these are: lactase (break down lactose-dairy), maltase & sucrase (break down food sugars), plus cellulase (break down cellulose and needed by those with food allergies ).
9. Where do we get enzymes?
Our body makes enzymes called metabolic enzymes. They are responsible for every action that takes place in our body including digestion.
Enzymes are found in raw foods. However, there are just enough enzymes in each particular food to assist in the breakdown of that food.
Supplemental plant enzymes are grown from food and measured by their action. They are sold in capsules or powder form. These enzymes can be ingested with food to assist in the digestion of food and the absorption of the nutrients. They can also be taken between meals to energize the body, fortify organs and build our biological defense system

16. Should children take enzymes?
Yes. Children usually eat the same enzyme-deficient foods as their parents. Breast-feeding is an important way babies receive enzymes. Children that are breast-fed acquire dozens of enzymes from their mother's milk. Bottle-fed babies receive pasteurized milk that has been heated, which destroys the milk enzymes. Drinking pasteurized milk causes the baby's enzyme factory to begin using its reserve of enzymes from day one. Research indicates that this could be harmful for the child. A study involving 20,061 babies was divided into three groups: breast-fed, partially breast-fed, and bottle-fed. They studied the morbidity (sickness) rate for the first nine months of the infant's life. They found that 37.4% of the breast-fed infants had sickness; in comparison to 53.8% of the partially breast-fed; and 63.6% of the bottle-fed. It is obvious that babies who were entirely breast-fed were healthier than babies who were only partially breast-fed or who were bottle-fed. They also examined the mortality rates of these different groups. The mortality rate among the bottle-fed infants was 56 times greater thanamong the breast-fed. In the United States one deformed child is born every 5 minutes, which is the equivalent of one in every ten families. This adds up to 250,000 deformed babies yearly. Dr. Andre Hakannson at Lund University in Sweden discovered that when he added mother's milk to cultured cancer cells that were alive prior to the addition of the milk, he soon found them to be dead. Further tests indicated that the milk killed only tumor cells, while normal adult cells were left intact. Research is trying to tell us that we, which includes pregnant women and children, must eat raw foods that contain enzymes and/or take supplemental enzymes.
17. Can enzymes control obesity?
Very definitely. Obese individuals were found to have deficiency in the enzyme lipase. Lipase is found in abundance in raw foods. Cooking destroys lipase in raw foods. Lipase is the enzyme that aids the body in breaking down and storing fats. Without lipase, our fat stagnates and accumulates in our arteries, which could lead to heart disease. Lipase also helps us to burn fat for energy. By eating cooked foods, which have no enzymes, we will put weight on more abundantly than if we eat raw foods. For example, pig farmers will not feed their pigs raw potatoes because the pigs stay lean. Instead, the farmers feed the pigs boiled potatoes and the pigs become fat.
Another reason why enzymes reduce obesity is because cooked foods cause drastic changes in the size and appearance of the pituitary gland. Researchers have found that enzymes affect our hormone-producing glands and hormones influence our enzyme levels. Cooked foods cause our pancreas, thyroid, and pituitary glands to exhaust their enzymes to digest our food. This causes our body to become sluggish, leading to weight gain. Raw food calories are relatively non-stimulating to glands and stabilize body weight more so than cooked food calories.
24. Can enzymes help with psoriasis?
Many dermatologists have reported favorable results with enzyme therapy. In the 1930s researchers found they could treat Psoriasis by having their patients eat large quantities of raw butter. Raw butter contains large amounts of lipase. Recent research has also found that massive doses of lipase will help cure psoriasis. However, when large amounts of concentrated enzymes are used, it is essential that the patient be observed by a doctor with experience in this type of treatment.

(Note: all of the above are quotes from the linked resources)


http://www.007b.com/wonders_breastmilk.php

(Lipase in breast milk)
Fats in breast milk are practically self-digesting, since breast milk also contains the enzyme lipase, which breaks down the fat. Fat is the main source of calories for babies - and babies need LOTS of calories to grow well! Also, fat in human milk has large amounts of certain omega-3 fatty acids, which are important for brain development (provided the mother eats those good omega-3 fats herself).


http://www.askdrsears.com/html/2/T020800.asp

SELF-DIGESTING FATS
There's another reason why babies digest human milk so quickly: the fat in human milk comes with an enzyme, lipase, that breaks the fat down into smaller globules so this important nutrient can be better absorbed into the bloodstream. Fat is a valuable source of energy for babies, so the presence of lipase makes the fat in human milk more available. This is one of the reasons human milk is so good for premature babies, who need lots of energy to grow but whose digestive systems are very immature.


http://www.rawfoods.com/articles/benefits.html

(Juicing for Enzymes)
Or, for another example, consider fresh juice's ability to deliver another important group of nutrients, know as enzymes. Enzymes are your body's work force. Acting as catalysts in hundreds of thousands of chemical reactions that take place throughout the body, enzymes are essential for digestion and absorption of food, for conversion of food stuffs into body tissue, and for the production of energy at the cellular level. In fact, enzymes are critical for most of the metabolic activities taking place in your body every second of every day.
Fresh juices are a tremendous source of enzymes. In fact, the "freshness" of juice is one of their key features, because enzymes are destroyed by heat. When you eat cooked foods, whether its meal, grains, fruits, or vegetables, if the food is cooked at temperatures above 114 degrees, the enzymes have been destroyed by the heat. Since fruits and vegetables are juiced raw, the enzymes are still viable when you drink the juice.
Coincidentally, many of the phytochemicals that nutritional researchers are focusing their attention on are either enzymes, or more often, they are substances that help build or activate enzymes that play essential roles in protecting cells from damage.

(Note: All of the above quotes are from the linked resources.) Tweet