ProGest is a natural OTC progesterone cream. It is sold in many healthfood stores under the manufacturer name Emerita. Some natural healthcare practitioners carry it under the manufacturer Transitions for Health. It is the same product. Here is a link that will enable you to learn more about it.
Dr. John Lee did a lot of research and work with natural progesterone creams and you may be able to find out more information by running a search by his name.
PCOS? I'm not sure what you're referring to...it's early in the morning and my brain is still waking up.