How long does die off last for?

I have been taking paragone for 2 weeks and have been suffering a lot of aches and pains, sore throat, tiredness and generally feeling under the weather. Am guessing this is a die off reaction but am just wondering whether the die off symptoms should be gradually getting better, because they have been quite variable, and the last few days have felt worse than at the beginning.

About to have the 5 day break from paragone so hoping symptoms will subside then before starting second 15 days.