Yes Garcia you have answered all my questions openly and honestly. Thank you - it has really helped. It is just when you read posts like - I took Primal Defence for four days and now I feel much better - you begin to wonder what you have got and where you are going wrong. There are obviously different levels of toxicity i.e. some people are more sick than others. What was it about the exercise that gave you oral thrush? I understand the fatigue but not the thrush. Thank you for your help.