I had a look at the Permavite and it looks interesting. How long were you using that one? You say it was helping? I've been on the lookout for a very long time for a good leaky gut supp but I finally gave up because I had bad reactions to all of them ( more irritation and pain ). I once tried that Seacure stuff and the pain was awful! Yikes! Can you tell me more about the intestinal glandular complex in this? I am not familar with it. Thanks very much for your help.