https://www.zoetisus.com/products/horses/questhorse/index.aspx Info on moxi and moxi plus . I dial for a little over my weight I weigh 215 pounds and dial for 250 pounds . 1 dose per month no more. I add fenben 5 day double doses 2 weeks later . I worm every new moon with fenben and full moon with moxi plus . I started with just moxi for 3 months then took moxi plus for my forth month. Moxi kills adults that ivermectin and fenben miss . Moxi is excellent on L5 larvae (the red threads) where ivermectin and fenben are poor on . Moxi with prazi targets kidney area especially the main arteries going in and out (back pain area ) prazi works thru the kidneys carrying moxi in areas that are normally filtered by kidneys hitting an area that's hard to reach . I had many kidney infections during my 2 plus years of treatment most in first year . I did get one after my first dose of moxi plus in April , took 2 weeks of doxy felt great and haven't had a symptom or infection including itchy butt since May 2016 . i take 5 mg 250 pound dose of moxi per month . Human testing for moxi patients were givenup to 36 mg 1 dose with no ill effects . They are dosing humans for river blindness in Africa at the same rate as horses with excellent results .look up moxi and river blindness look up doxy and river blindness . Having doxy on hand when a kidney(back pain)infection erupt is a blessing . Hope this helps