Re: Blastocystis
Hi. Yes, thanks for those corrections. I technically meant specific smooth muscle contraction. You are right about nitazoxanide, a broad spectrum antiparasitc drug, although there is still lack of supporting data on long term effectiveness. It would definitely be considered for cocktail.
The problem is the ovoid cysts, which are very often confused with candidal yeasts as they grow and expand. They tend to appear as "budding". The cysts are very tough, and probe their environment. They are defensive against penetration, and somehow evade antibodies.
I have taken note, the mature granular forms of the
parasite tend to start shriveling up as they traverse near the end of digestive cycle, making them unidentifiable to the untrained eye. My experience is unique, as I have advantage to do time sensitive observations(benefit of having equipment in the immediate space).
If reactivated in properly prepared medium, some cysts will grow to their clinically recognizable shape and form. This is temporary, as they can biochemically detect environmental conditions, and will encyst until returned to viable surroundings.
Researchers have discovered the extracts from the B.javanica seed and from Quercus infectoria nut gall have extremely high inhibitory concentrations in vitro in comparison to metronidazole. And metronidazole resistance has been discovered in B. Hominis (although the genetic mechanism for this remains unknown).
As for the answer to your original question, I have not yet made a precise quantitative analysis of blastocystis stool infiltrates, but it is high enough to be considered a candidate for pathogenisis.
Shroom