It is safe to take on an empty stomach, but from any protocol I know of you are taking too much.
Does Dr. Sutter recommend that amount? I didn't think so, but I am not sure. Standard Process considers it a whole food supplement. I have been to many of their seminars and no one ever took that much of it. There are other synergistic supplements to replace missing nutrients. But not just Zymex 2. Yes, it kills bugs as Dr. Sutter refers to them. But slower is better. And maybe an applied kinesiologist to see what you need most would be helpful.