Tom, I weigh 200lbs right now. I did not activate it, but mixed it with almond milk. Diarrhea, and vomiting quit on Friday, within six hours of ingestion. I woke this morning with my stomach growling and my appetite has returned. At least I feel like eating. I have not had dizziness, heart palpitation or difficult breathing. I initially took this for a sinus infection I couldn't kick. My sinuses are still the same, sadly.