Hi hoping you still read this even though little late. May be interested to look into mthfr gene mutation issues, sounds complicated but it's not. Basically you can take buckets of folate/iron but your body can't process it due to gene issue. Effectively you end up depressed to some degree but main outcome is tiredness like nothing else. I'm talking fall asleep at traffic lights sort of stuff. Simple test which is widely done to check mthfr gene for a1298c or c677..... Not sure but u can google it. Get this issue looked into and fix by taking mthylfolate which is iron processed for your body - amazing . Hope this helps. Sharon