Sorry you have all this pain. Is it in the gallbladder liver area where u feel the pain?
I know that the mid forties are very hard for many women, and this is the worst time for us because of perimenopause/menopause and stone formation... which tends to happen around this time.
Just keep going with your flushes.. it will do u the world of good... but just wait at least 3 weeks between flushes, i think 4 weeks even better.