i don't know longterm... treating an inflammatory condition with something that's going to inflame the shit out of your lips seems kind of risky... you might be best to leave well enough alone and be content with the relief the cream is bringing you... you have to consider that it may not be the fordyce spots that caused your inflammation but the sebum itself... and the spots may just be a symptom of the sebum... i have a trillion fordyce spots on my upper inner lip... it doesn't look like much though, they are so concentrated that the skin in that area just looks a little whiter, i have never had any pain or inflammation accosiated with them... i really regret the chemical peel to try and get rid of them because that's what caused the mess i got myself into with ec.
i wish you the best of luck but carefully consider this.