Re: triclabendazole resistance...biochemistry questions.. need help.. c p450 inhibitors..

Thank you.
Yeah, I tried mms and honestly I couldn't tell that it did actually anything. So, I just stopped after one dose. I think the medication has to be adjusted to comply with how large an infection you have and where the infection is inside the body. I just find it cruel and unusual punishment that triclabendazole works for the best for this particular fluke but is the most suspectible to develop a resistance.

Thanks for the list. I will look into those. He didn't mention grapefruit juice though?? I consider that to be the highest natural cyp3a4 inhibitor that there is, according to what I've read.

http://en.wikipedia.org/wiki/Grapefruit_juice


Also, i read that bromelain can inhibit the cyp2c9 enzyme..

http://www.ncbi.nlm.nih.gov/pubmed/18256496


Who knows if this is accurate or if the results have been replicated. But, it should make a difference.

The other thing is the flavin mono-oxygenase enzyme... the fmo.. When this was inhibited the triclabendazole worked better for resistant flukes. Do you know of any herbs, meds, supplements to inhibit that one?
Thank you.
David

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