There will always be people that have problems with a supplement due to allergies, gmo's, toxins, vaccines, medications and etc.
No protocol can be perfect for everyone and each person must find their comfort zone.
Supplements usually come with fillers, flow agents and others and all these things have different frequencies from those of the original active ingredient.
The active ingredients have differing frequencies to those combined in natural foods, so these all become factors.
I have never met anyone that had an issue with magnesium or epsom salts, but anything is possible.