Have you tried testing you Vitamin/Hormone D level?! Do you get enough sun!? Antibiotics are probably at play here too, disrupting your GI in the past.
Hormone D assists with restful sleep, something you're probably lacking. Without proper recovery, your body will always be in a sad state. Without proper nutrition assimilation, your body will always lack enough tools to fix itself.
Work on the gut bugs - forget all patented probiotics - and work on GOOD rest by getting enough sun or Vitamin/Hormone D if you're low. Synonymously, work on keeping gut bugs healthy by eating as pesticide, plastic, and Genetically-Modified-Organisms FREE.