I kind of gave up Scotty, I have spent over at least around $2000 - $5000 these past two years trying to figure this crap out.
I pretty much don't look into the mirror anymore and try to focus on healing the inner part first.
One thing that I do notice that speeds up the collagen loss is when my face starts to feel extremely warm and irritated mainly from stress and stimulating supplements. The next morning I would see new wrinkles on my face.
Also I would be careful about the zinc intake cause when I take any amount of zinc alone for more than 10 days, I would develop red spider veins all over my body. That tells me it is using up my bio-available copper faster than it can chelate toxic copper.