Anecdotally, some people use hyaluronic acid for painful knees. It's a major component of chicken gristle (cartilage). The hyaluronic acid itself comes from rooster comb. It can sometimes have side effects, such as skin rash.
http://www.drpasswater.com/nutrition_library/Sardi.html
(I tried pasting the article, but it came in very messed up.)
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