Definitely something going on with hormones, intestinal damage, brain abnormalities caused by copper and heavy metals, possible permanent brain damage, allergens also. Cortisol, sex hormones, and thyroid hormones have a lot to do with this, though that may be a side effect of the copper and brain damage itself. Still they play their part.
My theories as of so far.
I deal with these symptoms severely, debilitatingly on a daily basis now for 3 months. But to a degree I have always had these problems for about 10 or 11 years.