Xylitol and Cancer
So, we have on RXlist and WebMD (which are syndicated together) and then echoed again on livestrong that oral xylitol taken daily in amounts > 50g causes tumor-growth, and therefore should be limited to some portion less than this.
Could that be entirely B-12 (which xylitol can inhibit I think) related or what?
I've already been through the literature a fair bit and have found nothing to indicate carcinogency of xylitol, infact quite the opposite with regard to mouth-sores and even hepatoma. All longterm studies I've viewed indicate that heroic "zill" (as I sometimes call it) gets the all-clear. Even a multi-generation rat study revealed nothing but "cosmetic" signs ( medline/7271602 ).
Another one I saw that did some extreme dosing both 10% and 20% showed what I have in my notes as "raised bone-density (higher serum Ca and alkaline phosphatase activity, lower levels of serum tartrate-resistant acid phosphatase versus control)." But let's be reasonable -- no one is going to eat that much even if it becomes the exclusive sweetener in this household after acclimation.
I've e-mailed WebMD about where they got their information and am waiting to hear back.
I figure to really put things in perspective if you consumed 50g white table
Sugar for 3 years you'd also end up pretty ugly, but I'm thinking there's more to it.
SO -- is this just a foul rumor, or can anyone confirm?