Yes! I have major allergies to dust, pollen, mold etc... I noticed an improvement in my allergies after my 2nd flush. I've done 6 total, and while I don't have complete 100% relief, they are sooo much better. I was such a bad case, taking Zyrtec, Singulair, Flonase, Astelin, and Duratuss, and still having horrible congestion, fatigue and recurrant sinus infections. Today, I still have to take my medicine, but I function like a normal person. I can go outside and enjoy myself. No more infections and horrible fatigue. I am hopeful with more flushes, I can eliminate or reduce my meds. But honestly, even if I am unable to, I am extremely pleased with my allergy improvement.