The use of glandulars and herbs for Adrenal Fatigue is widespread. Due to the lack of standardization and research, there is common consumer misinformation and misuse. While the proper use of glandulars and herbs has its place as part of the adrenal recovery program, its use must be under proper judicious guidance for best results because of frequent atypical responses elicited when such compounds are used.Glandulars and herbs, while exhibiting desirable adaptogenic and tonic properties, may become stimulatory in nature when entering a body whose adrenal function is compromised. The more advanced the Adrenal Fatigue, the more prominent the stimulatory effects appear. This is most commonly noted in those with advanced adrenal weakness. For this reason, what seems to be harmless use by one person can be toxic to another.