I had an issue with cracks in the corners of the mouth for over year, and nothing seemed to work. Tried numerous creams, zinc, iron, and a number of other things. Nothing worked until I tried a BIOTIN supplement. I've read a number of these posts, and haven't seen any mention biotin as a possible solution. If any of you haven't tried Biotin, try it. Biotin is fairly cheap, and it might be the solution. It's worth a shot. It's ridiculous that people have to deal with this problem and can't get a solution from doctors. Hopefully this message helps some people.