I am one of those aggressive users who likes experimenting. I jumped up 2 drops (eye dropper size) twice a day to see what would happen. Nothing much happened for the first 6 days and I felt really good, but when I got to day 8 and 16 drops it really hit me. I got the big D in huge way. I was also taking the morning dose on on an empty stomach so that didn't help either. I felt pretty good except for an uneasy stomach and the big D. When I got a lot of blood on my BMs, I thought I better stop taking it in such large doses. That was yesterday and I haven't taken any today or had any need for a BM and I feel exceptionally good today. Better than I have in years and I am a very fit person with no known health problems. Today I felt like running everywhere I feel so good.
The lesson I got out of it is do it in moderation, which I will now do. I will be starting again tomorrow and cut my dose back to between 5-10 eye dropper drops once a day after a meal and most likely at night. I love the stuff and how it makes me feel.