I have been using Clark's parasite Program for about 25 years and repeat it regularly beside taking some of the other herbs she sugested. It is my opinion that taking the suggested amounts are not harmful. If this is your frist parasite program don't use the instructions on the bottles but find her protocol which starts you at a very low dose and builds up to a full dose over about 3 weeks. This helps you avoid toxic reactions as the parasites are killed off. I also use Clark's zapper which makes the program more effective.