i take nexium for the heartburn its a scriipt from my Dr,the progesterone cream i use is called Natural Woman i buy from GNC stores or you can order it online I was using a 1/4 teaspoon twice a day from day 14 until you start your period then after two months you just use an eighth of a teaspoon twice a day until you don't need it anymore this month i only needed to use it from day eighteen on because i didn't really feel i needed it so hopefully there is light at the end of the tunnel and i won't need it at all next month! It really made my anxiety and other symptoms just disappear:)i wish i had tried it sooner but i was scared hope this helps let me know if you need any other info