Wow, 41 flushes. Well, there may be a problem with the digestion of fats that is causing more to accumulate? Either that or the damage was extensive. It's also possible that a few of those flushes were not done with an ideal protocol. I know this happened to me. At least 2 of them were wasted efforts. Mostly this was due to lack of preparation with the malic acid, and other times I would skip (for some weird reason) the epsoms. Not recommended! I know it's possible to get a good flush without that, but this is the exception rather than the rule, and eventually backfires.
Wow, 41. Well, I've done 25, but only five in a row, so to speak. I think the first 20 which were done once a year did help, but they never did get to the deeper levels. Better than nothing, but I consider myself to have done five. They are also getting more productive as my preparation is consistent now.