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Re: Calcium, Iodine and Phosphorus Distributions in Human Thyroid Glands by Electron-Probe Microanalysis1
 
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Published: 15 y
 
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Re: Calcium, Iodine and Phosphorus Distributions in Human Thyroid Glands by Electron-Probe Microanalysis1


following up on this:

"emphasizing magnesium instead of calcium. In the author’s experience, megadosing with calcium (2,000-3,000 mg/day) has been the most common cause of poor response to orthoiodosupplementation."

http://jcem.endojournals.org/cgi/content/abstract/32/6/786


The distributions of calcium, Iodine and phosphorus in human thyroid glands (normal, hyperthyroid, multinodular adenomatous hyperplasia and follicular carcinoma) were determined by electron-probe microanalysis. Unexpectedly, calcium is heavily distributed throughout the colloid material but is even more concentrated in the epithelial cell lining. Some glands contained very high calcium concentrations in localized areas. Some types of goiter and psammoma bodies may be caused by a disturbance of the normal calcium metabolism of the thyroid. Iodine is rather uniformly distributed throughout the colloid material, and the range of Iodine concentrations in follicles from the same section is within a factor of 2. Phosphorus, indicative of epithelial cells, is heavily and widely distributed in multinodular adenomatous thyroids and in thyroids containing follicular carcinomas. The lack of coincidence between the follicular distributions of calcium and phosphorus clearly shows that the calcium in the colloid is not present as calcium phosphate.

 

 
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