I've used DMSO several times this week for an injury to my left knee ligament. I do not know how long ligament injuries take to heal. I am sure it depends on the severity, but after a few days it is all better. I used DMSO 3 times using a Q-Tip to finely spread the DMSO over the surface of the knee cap. DMSO is known to increase blood circulation, increase healing potential and many other things.