ABSOLUTELY! I always take the cayenne tincture in a 'gulps worth' of water (Rocky53 uses juice/cider)...and all tinctures CAN be taken with water or juice.
Sometimes with the liver tincture, I take it 'straight', because I want my tongue to get the full effect of the bitter herbs (as the bitterness is what stimulates the liver). But, for most, it's PLENTY bitter even if it's diluted by water/juice.
That Blood-Detox tincture is THE 'strongest' tincture I've ever made or tasted. I can't imagine taking that one without some water to dilute it!