one could take NPN in all kinds of directions... look at plastics and all the problems they have been shown to cause - melamine being used in them, among other NPNs.
That nitrogeneous compounds and waste causes the "dead" zones in the oceans, or die back in trees\plants, etc. etc. is a given, which then affects the earths ability to deal with increasing rates of CO2... it is that simple.
boosting nutritional levels "buffers" the effect. A low brix food is like eating non-nutritive\empty calories.
EDIT - think about it... we release CO2 as a waste gas... if we are unable to do so due to a burden if nitrogenous compounds\toxins... well the same issue exists as in planet respiration... not that hard to think through.