Of particular interest is the Side Effects section which depicts the consequence of a niacin deficiency and a large dose of niacin,
A deficiency of niacin causes pellagra. The symptoms include inflamed skin, digestive problems, and mental impairment.
Large doses of niacin can cause liver damage, peptic ulcers, and skin rashes. Even normal doses can be associated with skin flushing. It can be prescribed as a treatment for elevated total cholesterol and other types of lipid disorders, but it should only be used with medical supervision due to its potential side effects.