MSM is just another supplement...u can get it in powder or pill form. Sometimes, glucosamine or condroiton come mixed with msm already. Either way, MSM is best taken with a bit of vit. C....I prefer the powder, so get it and the vit. c powder, mix in water or juice and drink it down....one side effect is it will make your nails grow stronger and faster...and if your stomach gets upset, usually that means you put in too much vit. c powder...
I'm not sure how it works....but it works fine for my knee and ankle probs, along with glucosamine...