Hopefully you have read all the FAQs on detox on the other forum. I have been taking high doses since April. I have had no problems, except a couple of "colds", which in my mind were cleansings. I have had vision improvements, and I have gotten off all my medications since July. I also got rid of my fibromyalgia - hallelujah - no more pain!
The big caution in taking high doses is to manage the detox. It requires good elimination (3 BMs per day) and breaks to let the body catch up with the massive eliminations.