Not that I am 100%, but I have to say that after doing The Master Cleanse for 42 days (had to add potassium broth to rid myself of the severe intestinal cramping and the leg spasms), then Schulze's colon cleanse, then the liver cleanse, then the kidney cleanse and then the liver flush, I feel better. My Arthritis pain and my fibromyalgia pain and spasms are 50% better. I have continued to eat with no refined foods (yep, no bread, no pasta, no dairy) with only whole grains gently cooked to pop open, 5-6 servings of vegetables daily, 2-3 fruits daily (local and in season -- should be organic) and I have kept the pain level down. Still chronically painful and fatigued, but at way better controllable levels. I will be jumping back on Master Cleanse in a few days and will work at repeating the whole process one day when I have some more money to invest. That's how good I feel. I'm going to do the incurables program per Dr Schulze's suggestion if you have Arthritis or fibromyalgia. (I also have viral hepatitis with cirrhosis of the liver--so I cannot play around if I want to be healthy again). Success! DAR