Reactions to GABA and SAMe - why? 
#46136
11 y
7,420
Hi Dennis,
First off, many thanks for the very informative articles you've posted, they're really helpful.
I am trying to figure out why i have a bad reaction to GABA and SAMe.
I'm not on any medication, nor have been for over a decade - minimal nutritional supplements only.
GABA i wanted to use to help ease anxiety - i have the Phenibut form of it that passes the BB barrier quicker/easier. It is suggested to take 3 250mg caps a day but i barely tolerate one.
I find 250mg extremely tranquilising and sedating, eyes barely able to keep open, cannot hold my head up. What would cause such a strong reaction to what's considered a 'relaxing dose' for everyday activities?
SAMe - again wanted to use it for liver health, easing of depression, sense of calm - but instead one 400mg tab made me irritable, agitated, no mental focus, headache, listless, and extremely depressed!
I don't understand these paradoxical reactions.
I'm have very low adrenal function, hypothyroid, hypoglycemia. All being treated at a very slow pace with diet and supplements currently.
Any advice would be hugely appreciated.
More
- Re: Reactions to GABA and SAMe - why... dennishardyND
11 y
6,589
MoreThis is a reply to # 2,031,857anyone can have a reaction to anything. i would try one at a time and only half the dose.
also tell me about your diet, lifestyle, bowel habbats etc as all play a part. you can't live and eat poorly and exspect a little pill to solve your problem, the thing you are using are supplements to a healthy diet and lifestyle not subtatute for it- Re: Reactions to GABA and SAMe - why... #46136
11 y
6,467
This is a reply to # 2,031,933Yes absolutely, understanding the notion of diet and lifestyle for health are essential to wellness - a practice i have been engaged in for 20 yrs.
I rarely take supplement/pill until this health crisis. I also advocate there's no such thing as a magic bullet.
I've been raw vegan for many years, vegetarian before that - only including eggs and goats cheese, no meat/fish consumption for over 15 yrs. i'm not a beans and rice vegan either...plant based whole foods has been my focus nutritionally.
Lifestyle - rural wilderness living, run an organic farm, WAS very pysically active, took time to enjoy walks, reading, sculpting, animal care.
Adrenal issues have me increasing my protein so now i'm vegetarian again.
Regarding the SAMe and GABA - i took them seperately as im well aware of my hypersensitivity to even supplements so initially take anything on it's own to gauge results.
I just wondered if you had come across the paradoxical reactions i mentioned before with those specific supplements and possibly what caused them?
Many thanks.- Re: Reactions to GABA and SAMe - why... dennishardyND
11 y
6,510
This is a reply to # 2,032,021SAMe is not my first choice for liver health. A better choice for liver health would be milk thistle as directed on the label and try to stay away from any suppleents that do not agree with you. your better off useing whole foods or herbs anyway
- Re: Reactions to GABA and SAMe - why... dennishardyND
11 y
6,510
- Re: Reactions to GABA and SAMe - why... #46136
11 y
6,467
- Re: Reactions to GABA and SAMe - why... Plueschy
10 y
5,494
This is a reply to # 2,031,857Phenibut and SAM-E (oder SAMe) seems to interact some kind of strange.
I take 400-600 mg auf Sam-E at the moment and today I took 500mg of Phenibut. Normaly i 500mg ar barley noticable, but today i am very dizzy and sleepy.
(I am not a native englisch speeaker, so don't be too strict with my english please)
- Re: Reactions to GABA and SAMe - why... dennishardyND
11 y
6,589
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