Based on my experiences of just doing my second flush, the second was more successful in that more stones came out and were larger in general. I have not had the severe indigestion and pain as before. (Mine is liver pain, had my GB out last year before I knew better). I plan on flushing every two to three weeks. I am taking liver support herbs/teas, flax seed oil 1 tablespoon every day, drinking kombuchu tea, and doing all I can to help my liver work better. Good luck to you.