it depends on how much bromine is stored. it is clear to me it stores in fat. therefor, your body mass index is going to come into play. i have been at it since the beginning(6 months? i lose track) and i am still getting the pee and the zits. my fat was aweful, simply aweful. i had cleaned up most everything else. i am not real fat in appearance, but i was not real muscular due to all the down time i had since the mid nineties. i carried a lot of fat subcutaneously and in places it didnt show, like my back. i now have love handles, not because of gaining them, but because the fat on my back has melted away and i am losing weight. also, my muscle mass and tone is increasing with little effort on my part. i attribute this and my renewed energy and endurance to Iodine alone. its all i have been doing different.