Hi
I did not start wiht 50 but worked up to that amount. My history was taking anitbiotics that made me worse and so hospital visits etc,.. To cut a very long story short. I figured out that all the pain kilLers I HAD to take had a residue still in the colon. And the fact that a lot of them made me constipated over time as well.
After what came out from taking 50 pills, I was right about 8 inches of my colon was spastic. So I continued to take a lot just to get some action everyday otherwise I had the worse migraines on the planet and needed to stay in work just to survive.
I found that doing a mixture of foundational program and liver flush was the way forward for me and then going 2/3 liquid/raw food for 5 days at a time.
If your colon was seriuosly blocked you would be in Hospital or totally unable to digest anything - I saw my nan go thru that it was awful.
Dont know what you have experimented with so far but using the Dr. S ideas and playing with them more so is the best I have seen so far.