it is strong with alcohol in it. i mixed it with a little water, held it under my tongue for a while and then swallowed it. i dont remember if i did it on an empty stomach at first or not. i would think that would be best. i have no idea where the instructions are that he sent. i think he puts all that on a disc now. you can always call brenda and ask her. she is very knowledgable. 903-666-6107