an allergic reaction is dehydration or acid accumulations and toxic morbid matters(undigested rotting food) stored in the tissues. oregano oil will do the same thing. they also both will cause this leaky cell thing. neither should be used to excess and both can have tolerences built up to them. one drop per day is all i have ever heard anyone suggest as an ongoing therapy or lifestyle choice. this does not count commercial sites selling the stuff. i am sure melaluca company would love you to use a bottle a day.