You may not need to take this my wife had hysterectomy also and they where going to put her on some estriol replacemnet. Her sister found out about and told here about some home test you can order and take at home. When she got the test back she found out the she needed more Progesterone the Dr. was wrong with what he wanted to give her. Now she takes Natural Progesterone, I would say for more info go to this site