I am a 38 year old woman who had a complete hysterectomy at the age of 31 due to pre-cancerous cervical cells and endometriosis. I have been on Premarin ever since but recently have suffered from severe breast tenderness. I've also had weight gain, sore joints, memory loss, & dry skin with loss of elasticity. I am now on oral black cohosh and have ordered progesterone cream and estriol cream. I haven't received the products yet. Does anyone have experience with the estriol cream? Thanks