I'm in agreement with everything blueskyz had to say. But unfortunately I can also tell you from experience. 1st time I ever did the Master-Cleanse about 5 days in or so I had about 1 1/2 glasses wine - thinking, oh it can't be that bad, I mean wine is practically good for you in a small dose right? Well not in this case. You will feel like hell!!! Not only does it taste kind of funny but I got a monster headache, all-over yucky feeling - unclean almost, and though not puking, definitely not a happy stomach. I went right back next day but felt like I had lost 3. And at the time I drank plenty of wine usually. Trust me - it's not worth it. If you really want to celebrate your birthday and not worry about the drinking, just wait until next week to start MC. That's what I would do :)