This participation can be made conscious via the instrument that alchemists called the artifex, and I call the imaginal body. You imagine what is happening in your body, such as blood circulation, using an image, and then meditate on that image until you experience what is in fact already happening to you. The artifex, not the alchemist, achieves the Great Work. The imaginal body enables us to participate in what we initially picture, if we can picture it with sufficient depth and devotion. All that is done for us naturally and without our knowing, we can do with nature in full knowing.
The secret of the Art is to phase over by imaginal technique (the artifex) from being unconsciously inserted in nature to conscious engagement with nature, i.e., to coevolution. This was also one of the primary aims of the Mysteries whose adepts were dedicated to the Wisdom Goddess embodied in the Earth: Sophia.