I don't know too much about the thickness issue. I am going to the surgeon on March 31st and I'll ask about that. All I have heard about large stones is that they can cause major problems if they get through the wall of the gallbladder. There is a post on this happening to someone who is having problems. I am encouraged by your efforts to try and cure yourself. I am planning on starting a parasite cleanse this weekend and moving on from there. I am taking it slowly because I am affraid I will end up having a bad attack and ending up in the emergency room begging for surgery! I'm a little nervous but I guess you have to make a good effort before you give up.