Thanks everyone for your input. I must admit that I am not a good water drinker, but I know I must make a better effort there. I am supposed to take 2 pills in the AM then 2 in the PM. Next week double the dose, then week 3, triple the dose. I feel like a walking zombie when I take it in the AM, so I've been holding off till mid-day. I hope it doesn't make that much of a difference. I wish I could take them all at night and sleep thru it. Thanks everyone for your support.