Well, I wouldn't start digging those holes in the ground just yet. Edgar Cayce himself has said many times that changes which are indeed quite possible, will take about 100,000 years. They do not and will not happen overnight. So as much as it may sound scary - poles shifting, earthqakes happening, landmasses moving, climates changing - it will not come overnight. It will take at least a few thousand years.
Maybe a minor Goddaming is possible, due to human's own stupidity; nuclear war, another Chernobil, or some similar disaster. But those things can be prevented if we all start working on ourselves, and instead of fearful we become responsible.