I do experience pain in and around my liver quite often. When I first found CureZone it was chronic pain in between my shoulder blades - it just wouldn't quit. After my first flush it was gone, but came back later. Sometimes it was closer to the neck and upper shoulder; other times in the lower region. Last week-end after a very successful flush - which by the way, produced some gems that looked alot like Spock's motherlode, my liver was very tender for several days. I still have a long way to go before I'm done - you just keep on flushing and don't give up!!! Tina