I don't have any personal experience of either product. I've been doing the P&B shakes with the parasite cleanse and thought I'd add it to my program. So the advice I 've got ton so far was that using either poduct creates a wash out effect with the P&B shakes. I think colosan and Oxypowder are similar products that create oxygen in your colon. So you just need to use one at a time. I think colosan is $25.00-$30.00 and Oxypowder is $40.00-$50.00 and I've heard both are good products.